Microbiome analysis from ORY – Why a microbiome test is so valuable.
A modern Microbiome analysis Today's tests show you much more accurately than traditional stool tests how balanced your gut microbiome really is. microbiome test It analyzes the biodiversity, the balance of important bacterial groups, enterotypes and metabolic markers – thus providing a deep insight into your gut health.
Why is a microbiome test so valuable?
A balanced gut microbiome is one of the most powerful factors influencing digestion, the immune system, stress regulation, energy levels, and even mental strength. With a modern microbiome analysis, you gain a precise picture of your individual gut health – scientifically sound, detailed, and directly actionable. A professional microbiome test shows you not only which bacteria are present, but also how they function, which metabolic processes are active, and where your system needs support.
More and more people are consciously choosing an ORY microbiome test to specifically optimize their health, prevention, and performance. The analysis provides valuable parameters such as diversity, enterotype, butyrate production, mucosal barrier, H₂S production, histamine, inflammatory tendencies, and metabolic signatures.
What does a modern microbiome test reveal?
The molecular genetic analysis of your stool provides precise data on bacterial phyla, metabolic profiles, and key pathogens relevant to health – as documented in your lab report. This includes:
- Diversity (species diversity): A high value such as 6.45 indicates a stable, diverse microbiome – a strong factor for resilience, metabolism and intestinal barrier.
- Enterotype: The classification – e.g., to Bacteroides – describes the metabolic direction of your microbiome.
- Dysbiosis Index: Assesses how much your microbiome deviates from a healthy balance.
- Firmicutes/Bacteroidetes ratio: Shows the balance in the metabolic profile, often relevant for weight, energy and inflammation.
- Mucosal bacteria such as Akkermansia & Faecalibacterium: Both are important for inflammation control and the intestinal barrier – some of which are reduced in your findings.
- Butyrate-forming agents: Essential for energy, regeneration, and mucous membrane health. Some values are below the normal range.
- Metabolic markers (metabolome): Indications of bile acids, histamine, phenols, TMAO – important for detox, liver, cardiovascular system, and nutritional tolerance.
This combination makes the microbiome test particularly valuable because it not only explains symptoms but also provides concrete starting points for nutrition, lifestyle and therapeutic measures.
When is a microbiome analysis useful?
A professional microbiome test is particularly helpful if you:
- You have recurring digestive problems
- Do you experience low energy or inflammatory processes?
- you want to strengthen your immune system
- suffering from stress
- You want to improve your intestinal barrier
- If you want to optimize athletic performance, regeneration, or longevity
The data from the microbiome analysis clearly shows how individually your body reacts – and how strongly diet, stress, age and lifestyle shape the microbiome.
Why is a microbiome test particularly helpful?
Microbiome testing offers a modern combination of diagnostics, holistic therapy, and lifestyle-oriented medical coaching. A scientific microbiome test can be perfectly integrated into a prevention or longevity program – for example, for:
- Intestinal structure
- Nutrition concept
- Stress Regeneration
- Sports optimization
- Detox support
- Skin and hormone balance
Microbiome analysis thus becomes a real tool for actively shaping health – instead of just treating symptoms.
Scientific sources
1. Bifidobacterium longum – immune modulation
Source: Gavzy SJ et al. “Bifidobacterium mechanisms of immune modulation and …” 2023.
Link:https://pmc.ncbi.nlm.nih.gov/articles/PMC10730214/
Scientific description: This review summarizes how bifidobacteria (e.g., BB longum) influence the immune system – e.g., by reducing pro-inflammatory metabolites such as trimethylamine, promoting regulatory immune cells, and altering cytokine profiles.
Significance: This shows that bifidobacteria are an important component of a healthy intestinal barrier and a well-regulated immune system. Relevant for prevention: Increasing bifidobacteria levels can help reduce inflammation and stabilize the immune system.
2. Microbiome ↔ Mitochondria – Crosstalk
Source: Zachos KA et al. “The interplay between mitochondria, the gut microbiome and …” 2024.
Link:https://pmc.ncbi.nlm.nih.gov/articles/PMC11306032/
Description: This review examines the interaction between the gut microbiome and mitochondrial function – how microbial metabolites affect mitochondria, and conversely, how mitochondrial states affect the microbiome.
Significance: For energy metabolism and preventive diagnostics: it turns out that a dysbiotic microbiome not only has a local effect, but also intervenes systemically in cell energy processes.
3. Microbiome increases mitochondrial respiration in brain model
Source: Morais LH et al. “The gut microbiome promotes mitochondrial respiration in…” 2025.
Link: https://www.nature.com/articles/s41531-025-01142-5
Description: This original study in a mouse model shows that the gut microbiome increases mitochondrial activity in the striatum. The authors discuss whether this is compensatory or overactivating.
Significance: Specifically demonstrates the connection between the microbiome and mitochondria in the brain/nervous system – relevant for energy, neurotransmitters, mental health, and prevention.
4. Microbiome ↔ Energy production & immune response
Source: Clark A et al. “The Crosstalk between the Gut Microbiota and …” 2017.
Link: https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2017.00319/full
Description: This study shows that mitochondria respond to the gut microbiome by regulating energy production, altering the redox balance, and controlling immune responses (e.g., TNFα-induced).
Meaning: Underlines that gut health directly influences cellular energy, ROS balance and immune regulation – ideal for your diagnostic axes “microbiome-energy-immune system”.
5. Meta-analysis: Bifidobacterium probiotics & cardiometabolic parameters
Source: Chang KS et al. “Gut Microbiota and Liver Health: Meta-Analysis of Bifidobacterium-Containing Probiotics in NAFLD Management.” 2025.
Link: https://doi.org/10.3390/ijms26135944 (full link: https://www.mdpi.com/1422-0067/26/13/5944)
Description: This meta-analysis (RCTs up to the end of 2024) investigates how probiotics containing Bifidobacterium improve lipid profiles, blood pressure, glycemic control and inflammatory markers in NAFLD patients.
Significance: Demonstrates the direct benefit of targeted microbiome intervention in metabolic diseases – supports preventive diagnostics and therapeutic approaches within the framework of microbiome analysis.
