Neurotransmitters Serotonin Dopamine Cortisol Stress Sleep

Kryptopyrrole (HPL, urinary pyrroles)

The test measures pyrrole compounds in urine that are grouped as the haemopyrrole lactam complex (HPL) and colloquially called “kryptopyrrole”. They are associated with the metabolism of the blood pigment haem.

What lies behind the value

In complementary medicine it is assumed that these pyrroles bind zinc and vitamin B6 and are excreted with them (“pyroluria”, “HPU/KPU”). Zinc is a component of several hundred enzymes – for immune defence, skin and wound healing –, vitamin B6 is needed to make serotonin, dopamine and GABA. Pyroluria is not recognised as a disease in its own right in scientific medicine; the evidence is thin.

Raised kryptopyrrole – what does it mean?

In complementary medicine, a raised value is interpreted as a sign of increased loss of zinc and vitamin B6. Because this link is not established, it is more informative to measure zinc and vitamin B6 themselves.

Low kryptopyrrole – what does it mean?

A low value is unremarkable.

The interpretation is given in your report.

Also known as: kryptopyrrole, hpl, hpu, kpu, pyroluria, haemopyrrole lactam

Contexts in which this value is measured

  • Exhaustion
  • Mood swings
  • Frequent infections
  • Skin complaints

Analyses that include this value

There is currently no analysis in the shop for this value. A practitioner or doctor from the ORY expert network can tell you how else it can be determined.

View the expert network

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Reference ranges and how your personal value is to be read are set out in your findings report. You discuss the findings with a practitioner or doctor from the ORY expert network.