EPX (eosinophil protein X)
EPX – also called EDN (eosinophil-derived neurotoxin) – is a protein from the granules of eosinophil granulocytes. These immune cells are involved in allergic reactions and in the defence against parasites, especially worms. EPX is measured in stool.
What EPX does in the body
When eosinophil granulocytes are activated they release EPX. The protein can break down genetic material of viruses and cells (it is a ribonuclease) and damage parasites; in larger amounts, however, it also irritates the surrounding tissue. EPX in stool therefore shows how active eosinophil cells are in the gut lining.
Low EPX – what does it mean?
A low value is the normal case. It speaks against increased activity of eosinophil cells in the gut lining.
Raised EPX – what does it mean?
Raised levels show increased activity of eosinophil cells in the gut. This occurs with allergic-type reactions to foods, with worm infestation, with eosinophilic disorders of the digestive tract and with chronic inflammatory bowel disease. Which cause lies behind it is clarified by further tests in the treating practice.
The interpretation is given in your report.
Also known as: epx, eosinophil protein x, edn, eosinophil-derived neurotoxin, eosinophils
Contexts in which this value is measured
- Food reaction
- Abdominal pain
- Diarrhoea
- Bloating
- Itching
- Skin rash
Analyses that include this value
There is currently no analysis in the shop for this value. A practitioner or doctor from the ORY expert network can tell you how else it can be determined.
View the expert networkReference ranges and how your personal value is to be read are set out in your findings report. You discuss the findings with a practitioner or doctor from the ORY expert network.