Transglutaminase 6 antibodies (anti-TG6)
Transglutaminase 6 (TG6, neuronal transglutaminase) occurs mainly in nerve cells, especially in the cerebellum. The test measures IgA and IgG antibodies against TG6 in serum.
What TG6 does in the body
Like the other transglutaminases, TG6 cross-links proteins. In people with gluten intolerance, the immune system can form antibodies against TG6. These have been found in gluten ataxia – a disorder of balance and movement coordination originating in the cerebellum – and in other neurological complaints linked to gluten, even without gut symptoms.
Raised anti-TG6 – what does it mean?
Raised antibodies indicate a gluten-related immune reaction that may affect the nervous system. The marker is comparatively new and is assessed together with TG2 antibodies and the neurological examination.
Low anti-TG6 – what does it mean?
A low value shows no antibody formation against TG6.
The interpretation is given in your report.
Also known as: anti-tg6, tg6, neuronal transglutaminase, gluten ataxia
Contexts in which this value is measured
- Balance problems
- Tingling / numbness
- Headache
Analyses that include this value
There is currently no analysis in the shop for this value. A practitioner or doctor from the ORY expert network can tell you how else it can be determined.
View the expert networkReference ranges and how your personal value is to be read are set out in your findings report. You discuss the findings with a practitioner or doctor from the ORY expert network.