Omega-3

The omega-3 index measures EPA+DHA directly in the red blood cells (a three-month level). EPA and DHA are precursors of anti-inflammatory resolvins and protectins. How your value is to be read is set out in your findings report.

What omega-3 fatty acids do in the body

EPA and DHA are built into the membranes of all body cells; DHA is particularly abundant in the brain and retina. They make membranes more flexible and thereby influence receptors and signalling pathways. From EPA and DHA, cells make messengers that limit inflammatory reactions and initiate their resolution (resolvins, protectins, maresins). Omega-3 and omega-6 fatty acids compete for the same enzymes – the more omega-3 is incorporated, the fewer pro-inflammatory messengers arise from the omega-6 fatty acid arachidonic acid. The body converts plant-based alpha-linolenic acid into EPA only to a small extent and hardly into DHA.

Low omega-3 index – what happens in the body?

With a low index, there is less EPA and DHA in the cell membranes: relatively more pro-inflammatory messengers arise from arachidonic acid, and inflammation resolves more slowly. In studies, low values were associated with a less favourable cardiovascular situation, dry skin and mood swings. Causes are low consumption of oily sea fish and a diet rich in omega-6.

High omega-3 index – what does it mean?

A high index shows a lot of incorporated EPA and DHA, usually from a fish-rich diet or supplementation. Very high amounts can slightly delay blood clotting, which matters mainly when anticoagulant medication is taken at the same time.